ea0003p64 | Clinical Case Reports | BES2002
Fayers K
, Cox S
, Bower L
, Dyer R
, Dearman G
, Fahie-Wilson M
Macroprolactin(mPRL)is a high molecular weight form of prolactin(PRL)most commonly due to formation of a complex with IgG.The PRL in mPRL remains reactive in immunoassays for PRL and the complex has a longer plasma half life than monomeric PRL.mPRL is a common cause of hyperprolactinaemia but its origin is not known and the complex has minimal bioactivity in vivo.The clinical significance of hyperprolactinaemia due to mPRL is that it can cause diagnostic confusion and lead to ...